{"id":9933,"date":"2025-01-30T23:05:39","date_gmt":"2025-01-30T22:05:39","guid":{"rendered":"https:\/\/syva.es\/syvac-eh-marker-the-first-and-only-diva-vaccine-against-ehd-is-now-authorized-in-belgium\/"},"modified":"2025-01-31T08:06:14","modified_gmt":"2025-01-31T07:06:14","slug":"syvac-eh-marker-the-first-and-only-diva-vaccine-against-ehd-is-now-authorized-in-belgium","status":"publish","type":"post","link":"https:\/\/syva.es\/en\/syvac-eh-marker-the-first-and-only-diva-vaccine-against-ehd-is-now-authorized-in-belgium\/","title":{"rendered":"Syvac\u00ae EH Marker, the first and only DIVA vaccine against EHD, is now authorized in Belgium"},"content":{"rendered":"<p><strong>The FAMHP\/FAGG has just authorized Syvac<sup>\u00ae<\/sup> EH Marker, the first and only marker (DIVA) vaccine against the Epizootic Haemorrhagic Disease (EHD) virus.<\/strong><\/p>\n<p class=\"cvGsUA direction-ltr align-justify para-style-body\"><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Le\u00f3n \u2013 Parque Tecnol\u00f3gico \u2013 Spain, January 30th, 2025<\/span><\/p>\n<p class=\"cvGsUA direction-ltr align-justify para-style-body\"><strong><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Syva is pleased to announce that the FAMHP\/FAGG has granted emergency use authorization for its marker (DIVA) vaccine against EHD in accordance with Article 110(2) of Regulation (EU) 2019\/6 for use in cattle and deer.<\/span><\/strong><\/p>\n<p class=\"cvGsUA direction-ltr align-justify para-style-body\"><strong><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">SYVAC<sup>\u00ae<\/sup> EH Marker is the first and only subunit vaccine available on the European market against EHD serotype 8. The &#8220;subunit&#8221; technology is a major asset for disease control, enabling the implementation of a DIVA strategy that makes it possible to differentiate animals infected by the wild virus from vaccinated animals. <\/span><\/strong><\/p>\n<h6><strong>Why this temporary authorization?<\/strong><\/h6>\n<p>The Belgian authorities have granted this authorization based on the following elements:<\/p>\n<ul>\n<li>Several reports indicate the <strong>presence of biting midges<\/strong> in France, and this activity is highly likely to spread to Belgium. As a result, <strong>large-scale outbreaks could emerge starting in spring 2025<\/strong>.<\/li>\n<\/ul>\n<ul>\n<li><strong>Early vaccination is necessary<\/strong> to prevent the spread of large-scale outbreaks.<\/li>\n<\/ul>\n<ul>\n<li>Currently, no vaccine has marketing authorization in Belgium or any other European Union member state.<\/li>\n<\/ul>\n<ul>\n<li>Scientific studies show that <strong>there is sufficient data<\/strong> on the <strong>safety<\/strong>, <strong>quality<\/strong>, and <strong>efficacy <\/strong>of <strong>Syvac<sup>\u00ae<\/sup> EH Marker<\/strong>to authorize its temporary use.<\/li>\n<\/ul>\n<p>As a reminder, <strong>vaccination<\/strong> of cattle against serotype 8 of EHD is <strong>mandatory since January 1, 2025<\/strong>.<\/p>\n<h6><strong>Why is Syvac<sup>\u00ae<\/sup> EH Marker different from a conventional vaccine?<\/strong><\/h6>\n<p>The vaccine targets the <strong>VP2 protein<\/strong>, which plays a key role in the <strong>recognition<\/strong> and attachment of the <strong>virus<\/strong> to host cells. Therefore, <strong>antibodies induced against VP2<\/strong> are able to neutralize the virus. <strong>VP2 is the only protein of EHDV known to induce a strong response in the form of virus-neutralizing antibodies. <\/strong>A VP2 <strong>subunit vaccine<\/strong> therefore induces a focused protective response while an immune response against other viral proteins (e.g. VP5, VP7) confirms either a previous natural infection or vaccination with a conventional vaccine, without being able to distinguish between infected and vaccinated animals.<\/p>\n<h6><strong>Epizootic Haemorrhagic Disease: an imminent threat to Europe!<\/strong><\/h6>\n<p>The first cases of EHD serotype 8 were reported in November 2022, <strong>in Italy<\/strong>. Outbreaks were then detected in southern <strong>Spain<\/strong>, in Extremadura and Andalusia, and rapidly spread to many farms across the country. <strong>In September 2023, France reported its first outbreaks<\/strong>. As mentioned above, <strong>although EHD has not yet been detected in Belgium, vaccination has been mandatory there since January 1, 2025.<\/strong> The virus progression since 2022 suggests that no European country is safe in the future.<br \/>\nEHD does not affect humans. The virus \u2013 an Orbivirus \u2013 is transmitted by biting midges of the genus Culicoides, whose peak activity occurs primarily from July to October. <strong>For optimal herd protection<\/strong>, vaccination schedules should be completed <strong>before the Culicoides activity period<\/strong> and in compliance with <strong>vaccination good practices<\/strong>.<br \/>\n<strong>Vaccination<\/strong> is unanimously recognized as the most effective method for controlling the disease. Having a <strong>DIVA vaccine<\/strong> available for the first time in Europe is <strong>a significant breakthrough and a key innovation for protecting cattle herds.<\/strong><\/p>\n<h6><span style=\"text-decoration: underline;\"><strong>About Syvac\u00ae EH Marker<\/strong><\/span><\/h6>\n<p><strong>Syvac\u00ae EH Marker<\/strong> is the first and only <strong>subunit vaccine <\/strong>that provides differentiated protection against EHD in cattle and deer. It is currently the only vaccine on the European market that allows differentiation between infected and non-infected animals. Moreover, it is easy to use thanks to its two-dose vaccination schedule, with intramuscular injections of 2 ml given four weeks apart. It is available in 40 ml (20 doses) and 100 ml (50 doses) vials.<br \/>\n<strong>For more information, visit<\/strong> <a href=\"https:\/\/syva.es\/en\/producto\/syvac-eh-marker-injectable-emulsion\/\"><strong>the product page on this website<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Syva is pleased to announce that the FAMHP\/FAGG has granted emergency use authorization for its marker (DIVA) vaccine against EHD in accordance with Article 110(2) of Regulation (EU) 2019\/6 for use in cattle and deer.<\/p>\n","protected":false},"author":4,"featured_media":9920,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[789,791,797,2176,805,803,53],"tags":[2197,2196,2200,2206,2277,2307,2290,2289,2108],"class_list":["post-9933","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-animal-welfare","category-corporate-en","category-export","category-press-release","category-syva-in-the-world","category-syvastart-en","category-uncategorized","tag-diva-en","tag-ehd","tag-emergency-use","tag-emerging-disease","tag-epizootic-haemorrhagic-disease","tag-europe","tag-sub-units","tag-vaccination","tag-vaccine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Syvac\u00ae EH Marker, the first and only DIVA vaccine against EHD, is now authorized in Belgium - Syva<\/title>\n<meta name=\"description\" content=\"Syva is pleased to announce that the FAMHP\/FAGG has granted emergency use authorization for its marker (DIVA) vaccine against EHD in accordance with Article 110(2) of Regulation (EU) 2019\/6 for use in cattle and deer. SYVAC\u00ae EH Marker is the first and only subunit vaccine available on the European market against EHD serotype 8. 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SYVAC\u00ae EH Marker is the first and only subunit vaccine available on the European market against EHD serotype 8. 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SYVAC\u00ae EH Marker is the first and only subunit vaccine available on the European market against EHD serotype 8. 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