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VMD grants marketing authorisation for Syvazul® BTV3 in Great Britain

Syvazul® BTV 3 has obtained marketing authorisation in Great Britain for use in cattle and sheep, with a reduced dose in cattle.

León, 8 July 2025 – Syva is pleased to announce that Syvazul® BTV 3 has obtained marketing authorisation (Vm 31592/5006) in Great Britain, allowing its use in cattle and sheep to combat bluetongue virus serotype 3 (BTV-3). The authorisation, effective from 3 July 2025, is valid indefinitely.

A major update for cattle: reduced dose

A key breakthrough in this new authorisation is that the dose for cattle has been reduced from 4 ml to 2 ml, improving convenience and aligning with the latest regulatory data.

Reminder Indications and administration

-> Cattle

  • For active immunisation to reduce viraemia caused by BTV-3.
  • Onset of immunity: 3 weeks after completing the primary vaccination course.

Dosage (intramuscular):

  • From 2 months of age in naïve animals, or from 3 months if born to immune dams.
  • Primary vaccination: 2 doses of 2 ml, 3 weeks apart.

-> Sheep

  • For active immunisation to reduce viraemia, mortality, clinical signs and lesions caused by BTV-3.
  • Onset of immunity: 4 weeks after completing the primary vaccination course.

Dosage (subcutaneous)

  • From 3 months of age.
  • Primary vaccination: 1 single dose of 2 ml.

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